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內容編輯Enzolifesciences/Ghrelin monoclonal antibody (121)/BPD-ABS-052-121-1/1mg
分類: 最上層
發布時間: 1970-01-01 08:00
Product Specification:
| Clone: | 121 |
| Host: | Mouse |
| Isotype: | IgG2bκ |
| Immunogen: | Synthetic peptide corresponding to aa 14-28 of human ghrelin. |
| UniProt ID: | Q9UBU3 |
| Species reactivity: | Human, Rat |
| Applications: | ELISA, WB |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Ghrelin is an orexigenic (food intake stimulating) 27 or 28 amino-acid gut-brain peptide hormone produced by endocrine cells in the stomach, pancreatic islets and certain hypothalamic neurons. Two forms are produced by alternative mRNA splicing; Gln13 or 14 is missing from the second form. "Active" ghrelin is acylated (octanoylated) at Ser3; this form stimulates growth hormone secretion via GHS receptors and increases appetite. The des-acyl form does not have these effects but may have other actions. Plasma responses of total ghrelin to food may reflect those of active ghrelin. |